Shor‐Posner 2006.

Methods	RCT MT vs. placebo
Participants	54 male and female children (2‐8); HIV+, no AIDs symptoms; non‐hospitalised.
Interventions	Group 1: MT 12/52 2xpw for 20 min (various body areas) n=22 Group 2: placebo ‐ friendly visit 2xpw for 20 min n=25
Outcomes	CD4, CD8 and NKC counts.
Notes	More of placebo had decline in CD4 count (p=0.03); older children with MT had increased CD4+ (p=0.04); younger children with MT had increased NKC (p=0.05).
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	High risk	Sequence generation not stated.
Allocation concealment?	High risk	Not reported
Blinding? All outcomes	Low risk	Assessor may have been blinded as data were analysed in a laboratory and conducted by a machine
Incomplete outcome data addressed? All outcomes	High risk	Authors did not mention how they dealt with loss to follow‐up
Free of selective reporting?	Low risk
Free of other bias?	Low risk