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. 2010 Jan 20;2010(1):CD007502. doi: 10.1002/14651858.CD007502.pub2

Williams 2005.

Methods RCT
MT vs. MT+ meditation vs. meditation vs. control
Participants 58 male and female adults; late stage AIDS with/out co‐morbidities; hospitalised.
Interventions Group 1: meditation 4/52; n=13
Group 2: MT 4/52 5xpw for 30 min (various body areas) n=16
Group 3: meditation a/a plus MT a/a n=13
Group 4: control ‐ standard care (no MT or meditation) n=16
Outcomes QoL ‐ total score and spiritual sub‐category.
Notes MT+ meditation superior to single modalities/control for improved QoL‐transcendent and QoL‐total scores (p=0.01 and p=0.005 respectively)
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Low risk  
Allocation concealment? High risk Not reported
Blinding? 
 All outcomes Low risk mentioned that assessor was blinded
Incomplete outcome data addressed? 
 All outcomes Unclear risk Although intention‐to‐treat analysis was conducted, there was a disproportionate loss to follow‐up.
references  
Data and analyses  1 MT vs control  
Free of selective reporting? Low risk  
Free of other bias? Low risk