Date	Event	Description
2 March 2020	Amended	Clarification message from the Co‐ordinating Editor added to the Declarations of interest Declarations of interest statement about the review’s compliance with the Cochrane conflict of interest policy, which includes the relevant parts of the Cochrane Commercial Sponsorship Policy.
6 January 2014	New search has been performed	An updated search has been performed to 14 June 2013. No new trial has been included in this update and the overall conclusion of the review has not changed.
15 February 2011	Feedback has been incorporated	Added a link to the Cochrane Editorial Unit's report on feedback on anticoagulants reviews.
15 February 2011	New citation required but conclusions have not changed	New author added.
11 February 2010	Amended	Error in dates: 'assessed as up‐to‐date' and 'date of search' due to RevMan conversion has been corrected.
20 April 2009	Amended	Author details error due to RevMan conversion has been corrected.
8 September 2008	Amended	Converted to new review format.
8 February 2000	New citation required and conclusions have changed	Substantive amendment