Table 3.
Correlation of CTC detection with CS or CC and clinicopathological characteristics. P ‐values were calculated by Mann–Whitney test for numerical and the chi‐square test for categorical data
| Patient subset | CellSearch | CellCollector | ||
|---|---|---|---|---|
| ≥ 3 CTCs | P ‐value | ≥ 3 CTCs | P ‐value | |
| Age (years) | n (%) | n (%) | ||
| < 70 (n = 38) | 7 (18.4) | 0.617 | 7 (18.4) | 0.084 |
| ≥ 70 (n = 42) | 6 (14.3) | 15 (35.7) | ||
| Sex | ||||
| Male (n = 49) | 9 (18.4) | 0.519 | 13 (26.5) | 0.807 |
| Female (n = 31) | 4 (12.9) | 9 (29.0) | ||
| Primary tumor | ||||
| Location | ||||
| Colon (n = 37) | 9 (24.3) | 0.256 | 9 (24.3) | 0.952 |
| Rectum (n = 24) | 3 (12.5) | 6 (25.0) | ||
| Tumor stage | ||||
| T1/T2 (n = 11) | 0 (0.0) | 0.070 | 3 (27.3) | 0.819 |
| T3/T4 (n = 50) | 12 (24.0) | 12 (24.0) | ||
| Lymph node | ||||
| N0 (n = 22) | 0 (0.0) | 0.004 | 5 (22.7) | 0.800 |
| N+ (n = 39) | 12 (30.8) | 10 (25.6) | ||
| Distant metastasis | ||||
| M0 (n = 29) | 1 (3.4) | 0.002 | 9 (31.0) | 0.266 |
| M+ (n = 32) | 11 (34.4) | 6 (18.8) | ||
| UICC stage | ||||
| UICC I/II (n = 17) | 0 (0.0) | 0.016 | 4 (23.5) | 0.905 |
| UICC III/IV (n = 44) | 12 (27.3) | 11 (25.0) | ||
| Recurrent disease | ||||
| Local recurrence (n = 2) | 0 (0.0) | 0.725 | 0 (0.0) | 0.253 |
| Distant recurrence (n = 17) | 1 (5.9) | 7 (41.2) | ||
| Resection status | ||||
| R0 (n = 60) | 5 (8.3) | 0.001 | 17 (28.3) | 0.772 |
| R1 + R2 (n = 20) | 8 (40.0) | 5 (25.0) | ||
Statistical significant values (P < 0.05) are shown in bold.