Comparison 2. Black cohosh versus hormone therapy.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Vasomotor symptoms: daily hot flush frequency	2		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
2 Vasomotor symptoms: weekly hot flush frequency	1	44	Mean Difference (IV, Fixed, 95% CI)	26.42 [18.59, 34.25]
3 Vasomotor symptoms: hot flush intensity	2		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
4 Vasomotor symptoms: night sweats	1	112	Mean Difference (IV, Fixed, 95% CI)	0.93 [0.47, 1.39]
4.1 Night sweat frequency per day	1	112	Mean Difference (IV, Fixed, 95% CI)	0.93 [0.47, 1.39]
5 Menopausal Symptom Score	5	468	Std. Mean Difference (IV, Fixed, 95% CI)	0.32 [0.13, 0.51]
5.1 Kupperman Index	3	312	Std. Mean Difference (IV, Fixed, 95% CI)	0.20 [‐0.02, 0.43]
5.2 Greene Climacteric Scale	1	44	Std. Mean Difference (IV, Fixed, 95% CI)	0.25 [‐0.37, 0.87]
5.3 Wiklund Menopause Symptom Score	1	112	Std. Mean Difference (IV, Fixed, 95% CI)	0.77 [0.35, 1.19]
6 Adverse events	1	42	Risk Ratio (M‐H, Fixed, 95% CI)	0.83 [0.21, 3.24]