1. Participant characteristics.
Study ID | Treatment | Participant numbers | Male:Female | *Age when seizures started (years) | *Age when randomised (years) | Frequency of seizures on randomisation |
Andrade 2009 | Clobazam | 18 | 12:6 | Not clearly stated | 9.22 +/‐ 1.3 (7‐11) | Not given (6 or more per month) |
Carbamazepine | 25 | 10:15 | Not clearly stated | 8.4 +/‐ 1.3 (7‐10) | Not given (6 or more per month) | |
Coppola 2007 | Levetiracetam | 21 | 11:10 | 10.2 | 10.5 | Mean 1.8 per month |
Oxcarbazepine | 18 | 10:8 | 7.7 | 8.4 | Mean 1.5 per month | |
Kang 2007 | Carbamazepine | 54 | 32:22 | 8.0 | 8.7 | Not given |
Topiramate | 58 | 32:26 | 8.0 | 8.7 | Not given | |
Rating 2000 | Sulthiame | 31 | 16:15 | 7.6 (1.9 ‐10.4) | 8.2 (3.9 – 10.7) | Median 3 (2 – 10) during 6‐months |
Placebo | 35 | 24:11 | 7.7 (3 – 10.2) | 8.4 (3.1 – 10.3) | Median 2 (2 – 20) during 6‐months |
* Mean age (except study by Rating 2000, where median age reported)