| Methods | RCT (Randomised Controlled Trial); multicentre (Japan) | |
| Participants | Patients with Dukes A, B and C (TNM stage I, II, III) rectal cancer undergoing radical surgery of the primary tumor (n=447) | |
| Interventions | 2‐arm trial: patients randomly assigned to: A) surgery alone (n=229), or B) surgery + adjuvant chemotherapy (n=218) with Uracil‐Tegafur (UFT, an oral fluoropyrimidine) plus intravenous 5‐FU and MMC | |
| Outcomes | Disease‐free survival (DFS) and overall survival (OS) | |
| Notes | The data are from an individual patient data (IPD) meta‐analysis (Sakamoto 2007 (JFMTC15‐1)) since no original article has been published on this RCT | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment (selection bias) | Low risk | |
| Selective reporting (reporting bias) | High risk | Data from an IPD meta‐analysis (no original article) |
| Other bias | Low risk | |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.