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. 2012 Jul 11;2012(7):CD007986. doi: 10.1002/14651858.CD007986.pub2
Trial name or title Randomised controlled trial investigating effect of supplementation with omega‐3 fatty acids EPA and DHA versus omega‐6 fatty acid LA on ADHD symptoms and learning difficulties in 7‐12 year old children
Methods Cross‐over, randomised, double‐blind controlled trial of omega‐3 versus omega‐6 PUFA
Participants Inclusion criteria: 120 children aged 7 to 12 years, ADHD diagnosis, parent‐reported learning difficulties
Exclusion criteria: on stimulant medication, taken omega‐3 supplements for up to 3 months, haemophilia
Interventions 1 g eicosapentaenoic acid (EPA), 1 g of docosahexaenoic acid (DHA) or linolenic acid (LA; sunflower oil placebo) in 4 capsules per day) in a 3 x 3 cross‐over trial over 12 months
Outcomes Conners’ parent rating scales, cognitive assessments of attention, impulsivity and literacy at 0, 4, 8 and 12 months
Starting date 16 July 2007
Contact information Dr Natalie Sinn
Nutritional Physiology Research Centre, University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia
+61 8 83021757
natalie.sinn@unisa.edu.au
Notes Email sent 23 April 2012 to check on progress of study