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. 2019 Jun 26;286(1905):20191072. doi: 10.1098/rspb.2019.1072

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© 2019 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 4. — The effect of developmental hypoxia and experimental treatment on myofilament Ca²⁺-sensitivity. (a,b) Correlations between the calcium transient (Δ[Ca²⁺]_i) and cell shortening, in cardiomyocytes from juvenile turtles that embryonically developed in either normoxia (N21) or chronic hypoxia (H10). Plotted data represent normoxia (N), anoxia (A) and reoxygenation (R); N21 n-values = 26, 52 and 26 and H10 n-values = 22, 44 and 22, for normoxia, anoxia and reoxygenation, respectively). (c) Correlation between extracellular Ca²⁺ ([Ca²⁺]_e) and relaxed cell length (n = 32 and 24, for N21 and H10, respectively). (Online version in colour.)