Figure S4. Retained introns change the coding potential of longevity genes mdl-1, F13G3.6, and trxr-1.
(A–C) The mRNA (green features) and predicted CDS (yellow features) are shown for the genes (A) mdl-1, (B) F13G3.6, and (C) trxr-1 and their isoforms with retained introns that were translationally promoted under DR. Red boxes highlight the differences between the isoforms. The predicted translated sequence is given for the novel isoforms. (D) Box plots of expression of the NMD genes smg-1/2/3/4/5/6/7 under well-fed conditions (AL) or under DR in the total RNA (TO) fraction on in the translated (TR) fractions.