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. 2019 Jun 11;20(11):2850. doi: 10.3390/ijms20112850
DN Diabetic nephropathy
ESRD End-stage renal disease
ACE Angiotensin converting enzyme
ARBs Angiotensin II receptor blockers
LPA Lysophosphatidic acid
ATX Autotaxin
AGE Advanced glycation end (product)
GPAT Glycerol-3-phosphate acyltransferase
PLA1 and PLA2 Phospholipases A1 or A2
PA Phosphatidic acid
LPE Lysophosphatidylethanolamine
LPC Lysophosphatidylcholine
LPS Lysophosphatidylserine
LPPs Lipid phosphate phosphatases
MAG Monoacylglycerol
AGPAT Acylglycerophosphate acyltransferase
PLC Phospholipase C
DAG Diacylglycerol
MAPK Mitogen-activated protein kinase
PI3K Phosphatidylinositol 3 kinase
PKB Protein kinase B
ROCK Rho-associated protein kinase
RAGE Receptor for advanced glycation end products
Nox NADPH oxidase
PPARγ Peroxisome proliferator-activated receptor γ
CKD Chronic kidney disease
ECM Extracellular matrix
GBM Glomerular basement membrane
EMT Epithelial mesenchymal transition
CCL2/MCP1 Monocyte chemoattractant protein 1
CCL5/RANTES Regulated upon activation, normal T cell expressed, and secreted
ICAM-1 Intercellular adhesion molecule-1
VCAM-1 Vascular cell adhesion molecule-1
PAI-1 Plasminogen activator inhibitor-1
uPA and tPA Urokinase-type and tissue-type plasminogen activator
TIMP-1 Tissue inhibitor matrix metalloproteinase-1
JNK c-Jun N-terminal kinases
VEGF Vascular endothelial growth factor
SGLT-2 Sodium–glucose cotransporter-2
GSK3β Glycogen synthase kinase 3β
SREBP 1 Sterol regulatory element-binding protein1
TGF-β Transforming growth factor-β
TLR 4 Toll-like receptor 4
NF-KB Nuclear factor-KB
KLF5 Krüppel-like factor 5
Egr1 Early growth response 1
S1PR Sphingosine 1 phosphate receptor
GPR4 pH-sensing G protein-coupled receptor
OGR1/GPR68 Ovarian cancer G-protein coupled receptor-1