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Conserved synteny of the wcs1 genes. The phylogenetic relationships among placentals and the evolutionary time scale are based on TimeTree (33, 53). The solid and open circles indicate that the wcs1 gene homologs were identified by BLASTp and BLASTn/tBLASTn, respectively. The gene synteny of wcs1 is shown near the corresponding species. Genes with premature stop codons or frameshift mutations are labeled with asterisks.
