TABLE 2.
AI virus antigen staining in tissues from chickens inoculated by the intrachoanal route with H7N3 HPAI viruses
| Tissue | Result by virus (bird 1/bird 2)a |
||
|---|---|---|---|
| A/CK/JL/12 | A/CK/PB/15 | A/CK/PB/16 | |
| Nasal epithelium | +++/+++ | +++/+ | +++/+++ |
| Trachea | ++/+++ | ++/+++ | +++/+++ |
| Lung | +++/+++ | +++/++ | +++/+++ |
| Air sac | ++/+ | ++/+ | +/+ |
| Brain | ++/++ | +++/++ | +++/+++ |
| Heart | +++/+++ | +++/+++ | +++/+++ |
| Spleen | +++/+++ | +++/+++ | +++/+++ |
| Liver | ++/++ | +++/+ | +++/+++ |
| Kidney | ++/++ | +/+ | +++/+++ |
| Adrenal gland | +/+ | ++/+ | ++/++ |
| Skeletal muscle | ++/++ | ++/++ | ++/++ |
| Pancreas | −/− | +/+ | +++/+ |
| Cloacal bursa | +++/+++ | +++/++ | +++/++ |
| Cecal tonsils | +++/++ | +++/+ | ++/+++ |
| Thymus | +++/+++ | ++/++ | +/+ |
| Proventriculus | ++/++ | +/+ | +++/+++ |
a
The chickens were euthanized at 2 dpi. −, no positive cells; +, single-positive cells; ++, scattered groups of positive cells; +++, widespread positivity.