TABLE 2.

Effects of the D286R mutation in UL31 on HSV-1 growth in Vero cells when infected at an MOI of 0.01

Virus	Expt no. and statistic	Viral yields (PFU/ml)
		10 hpia	24 hpi	36 hpi	48 hpi
HSV-1(F)	1	3.0 × 102	9.0 × 105	1.2 × 107	2.5 × 107
	2	6.0 × 102	8.0 × 105	1.5 × 107	2.5 × 107
	3	1.5 × 102	1.2 × 106	9.5 × 106	3.0 × 107
	Mean	3.5 × 102	9.5 × 105	1.2 × 107	2.7 × 107
	SE	1.3 × 102	1.0 × 105	1.6 × 106	1.5 × 106
YK726 (UL31-D286R)	1	3.0 × 101	2.5 × 104	2.5 × 105	3.0 × 106
	2	2.0 × 101	2.5 × 104	8.0 × 105	1.5 × 106
	3	2.0 × 101	4.0 × 104	5.0 × 105	2.0 × 106
	Mean	2.3 × 101	3.0 × 104	5.2 × 105	2.2 × 106
	SE	3.3 × 100	5.0 × 103	1.6 × 105	4.4 × 105
YK727 (UL31-D286R-rep)	1	7.0 × 102	1.4 × 106	1.6 × 107	1.8 × 107
	2	8.0 × 102	7.0 × 105	8.5 × 106	2.7 × 107
	3	4.5 × 102	2.2 × 106	2.1 × 107	1.4 × 107
	Mean	6.5 × 102	1.4 × 106	1.5 × 107	1.9 × 107
	SE	1.0 × 102	4.2 × 105	3.5 × 106	3.8 × 106

^ahpi, hours postinfection.