FIG 3.
Nonreplicating MVAdelta5gp120 is not superior to conventional MVAgp120 for induction of serum gp120-specific IgG. Female rabbits were intramuscularly vaccinated with MVAgp120 or MVAdelta5gp120 at the doses indicated on days 0 and 21. The rabbits were bled on day 35, and gp120-specific and vector-specific (B5 and L1) IgG titers were determined by ELISA. *, significantly different from 1 × 108 PFU of conventional MVAgp120 (P < 0.05). The connecting lines represent the geometric mean titers.