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. 2019 Jun 28;93(14):e00405-19. doi: 10.1128/JVI.00405-19

TABLE 1.

Antibody characteristics

Antibody Heavy chain profilea
Light chain profilea
V gene J gene CDR3 sequence % germ line identity Isotype V gene J gene CDR3 sequence % germ line identity Isotype
AC4 IGHV1-2*06 IGHJ6*02 CARDRRSTWYFYYYGMDVW 99.1 IgG2 IGLV2-8*01 IGLJ2*01 CSSYAGSNIYVVF 99.7 Lambda
AC10 IGHV1-2*06 IGHJ6*02 CARDRRSSWYYYYYGMDVW 99.1 IgG1 IGLV2-8*01 IGLJ2*01 CSSYAGSNNFRVF 99.1 Lambda
AC11 IGHV5-10-1*01 IGHJ4*02 CARLGLTNYFDYW 98.8 IgG1 IGLV3-21*02 IGLJ1*01 CQVWDSSSGGVF 98.4 Lambda
AC3 IGHV1-2*06 IGHJ4*02 CARDHYGDSWHYVFDYW 97.9 IgG1 IGKV3-15*01 IGKJ2*01 CQQYNNWPRYTF 97.5 Kappa
AD5 IGHV1-18*01 IGHJ4*02 CAREYYDFWSGYYAYYFDYW 99.7 IgG1 IGLV2-14*01 IGLJ3*02 CSSYTSSSTRVF 99.1 Lambda
FA12 IGHV1-69*01 IGHJ4*02 CVRALYCSSTSCYAARGGYFDYW 98.2 IgA1 IGLV2-14*01 IGLJ3*02 CSSYTSSSTWVF 99.1 Lambda
FC11 IGHV1-18*01 IGHJ4*02 CAREYYDFWSGYSSYYFDYW 99.4 IgG1 IGLV2-14*01 IGLJ3*02 CSSYTSSSTRVF 99.7 Lambda
AA1 IGHV4-4*02 IGHJ4*02 CARDSQQLVPFDYW 98.2 IgG1 IGLV2-8*01 IGLJ3*02 CSSYAGSNNLRVF 99.4 Lambda
FC3 IGHV3-33*03 IGHJ4*02 CVREDYGIFTKFDYW 90.5 IgM IGKV1-5*03 IGKJ1*01 CQQYNSDSWTF 94.3 Kappa
GD12 IGHV1-2*06 IGHJ6*02 CARDRRSSWYYYYYGMDVW 99.14 IgG1 IGLV2-8*01 IGLJ2*01 CSSYAGSNNFRVF 99.4 Lambda
GA3 IGHV3-30-3*01 IGHJ6*02 CARDRSRDSSGYWLIYYYYYGMDVW 98.2 IgG1 IGLV1-47*01 IGLJ2*01 CAAWDDSLSGVVF 99.7 Lambda
EA7 IGHV3-21*01 IGHJ6*02 CARGGHRVDYYYNMDVW 96.2 NDb IGKV1-9*01 IGKJ1*01 CQQLNSYPLTF 95.3 Kappa
a

IMGT/V-QUEST software was used to assign the germ line reference for IGHV and IGLV genes and to determine percent identity to the germ line.

b

ND, not determined.