Table 2.
Antimicrobial properties of the lead molecules against S. aureus ATCC 33591 (Sa91), S. aureus ATCC 33592 (Sa92), S. aureus ATCC 43300 (Sa00), S. epidermidis 700296 (Se), A. baumannii ATCC BAA-1605 (Ab05) and A. baumannii ATCC 747 (Ab47). NA = no activity (compounds did not show any noticeable activity up to 50 μg/mL concentration).
| SN | Sa91 | Sa92 | Sa12 | Sa00 | Se | Ab05 | Ab47 |
|---|---|---|---|---|---|---|---|
| 7 | NA | 3.125 | NA | 3.125 | NA | NA | >25 |
| 8 | 6.25 | 3.125 | 6.25 | 6.25 | 6.25 | NA | NA |
| 11 | NA | >25 | NA | >25 | NA | >25 | 12.5 |
| 12 | 25 | 25 | >25 | 25 | 25 | 25 | 6.25 |
| 13 | >25 | 25 | >25 | >25 | NA | 12.5 | 12.5 |
| 14 | NA | 25 | NA | >25 | >25 | >25 | >25 |
| 15 | 12.5 | 12.5 | 12.5 | 12.5 | 12.5 | 3.125 | 3.125 |
| 16 | NA | 25 | >25 | 25 | 25 | 12.5 | 12.5 |
| 17 | 12.5 | 12.5 | NA | 25 | 25 | 6.25 | 1.56 |
| 18 | NA | >25 | NA | NA | NA | NA | >25 |
| 21 | NA | 3.125 | NA | 3.125 | NA | NA | NA |
| 22 | NA | 6.25 | NA | 3.125 | NA | NA | NA |
| 23 | 25 | 25 | 12.5 | 12.5 | 25 | 25 | >25 |
| 24 | NA | 6.25 | 6.25 | 6.25 | 6.25 | NA | NA |
| Vancomycin | 0.78 | ||||||
| Colistin | 0.78 | ||||||