Table 2.

Nuclear circularity and nuclear roundness measured by ImageJ software. The control samples were MCF-7 exposed to 37 and 43 °C for 24 h and 48 h without SiO₂@LA NPs exposure. The treated samples were represented by cells exposed to 10 μg/mL and 40 μg/mL for 24 h and 48 h and 37 °C and 43 °C.

		Nuclear Circularity	Nuclear Roundness
CTRL	24 h, 37 °C	0.91 ± 0.20	0.80 ± 0.05
	48 h, 37 °C	0.90 ± 0.01	0.79 ± 0.02
	24 h, 43 °C	0.89 ± 0.03	0.79 ± 0.04
	48 h, 43 °C	0.89 ± 0.02	0.78 ± 0.02
10 µg/mL	24 h, 37 °C	0.89 ± 0.04	0.81 ± 0.03
	48 h, 37 °C	0.85 ± 0.02	0.79 ± 0.09
	24 h, 43 °C	0.87 ± 0.07	0.83 ± 0.01
	48 h, 43 °C	0.80 ± 0.02	0.85 ± 0.04
40 µg/mL	24 h, 37 °C	0.88 ± 0.02	0.80 ± 0.04
	48 h, 37 °C	0.75 ± 0.04	0.83 ± 0.05
	24 h, 43 °C	0.80 ± 0.01	0.87 ± 0.03
	48 h, 43 °C	0.69 ± 0.02	0.88 ± 0.05