Figure 1.
An overview of working model of GLUT1: The function of GLUT1 depends on conformational change. The inward-open (IOP) conformation, green, was adopted from PDB ID: 5EQG; the outward-open (OOP) conformation, cyan, was constructed by homology modeling of PDB ID: 4ZWC; the partially outward occluded (POO) conformation, yellow, was constructed by homology modeling of PDB ID: 4GBZ; the outward-occluded (OOC) conformation, violet, was constructed by homology modeling of PDB ID: 4ZW9; the partially inward occluded (PIO) conformation, red, was constructed by homology modeling of PDB ID: 4JA3.
