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. 2019 Jun 3;20(11):2717. doi: 10.3390/ijms20112717

Table 1.

Effects of different types of exercise on SIRT1, SIRT3 and PGC-1α expression.

Type of Exercise Mode SIRT1 SIRT3 PGC-1α
Acute Wingate test [26] ↑ (Prot) - = (Prot)
SIT [27] - = (mRNA) ↑ (mRNA)
Stationary
bicycle [28]
- ↓(mRNA)
= (Prot)
-
Treadmill [29] ↑ (mRNA) (*S)
= (mRNA)
= (mRNA) (*S)
↓(mRNA)
-
Successive Bouts 3 bouts of
3 h cycling [30]
↑ (mRNA) - ↑ (mRNA)
HIIT 6 sessions low-volume [31] ↑ (Prot) - = Total (Prot)
↑ Nuclear (Prot)
7 sessions [32] ↑ (act)
= (Prot)
- ↑ Nuclear (Prot)
↑ Total (Prot)
18 sessions [33] ↓(Prot)
↑ (act)
- ↑ (Prot)
24 sessions
SIT [27]
- = (Prot) = (Prot)
Aerobic Training 24 sessions
Treadmill [34]
- ↑ (Prot) (*S) -
15 Sessions
one-legged knee extensor [35]
- = (Prot) -
36 sessions
Cycle ergometer [36]
- ↑ (Prot) (*S) (OW) ↑ (Prot) (*S) (OW)
Resistance Training 36 sessions
11 exercises for the major muscle groups [37]
- = (Prot) (*S) (OW) = (Prot) (*S) (OW)

Results observed in the vastus lateralis muscle sample of trained or recreationally healthy young people unless it is specified that they were sedentary (* S) or overweight (OW). Act, activity; HIIT, high-intensity interval training; Prot, protein content; SIT, sprint-interval training.