Table 2.

Comparison between the two groups in MoCA points and GCS scores before and after the treatment (Mean $\pm$ SD).

	HRT group ($n$: 68)		Control group ($n$: 68)		$p$-value a	$p$-value b	$p$-value c	$p$-value d
	Before	After	Before	After
Visuospatial/Executive	5.91 $\pm$ 0.99	6.24 $\pm$ 1.01	5.96 $\pm$ 0.94	5.97 $\pm$ 1.02	0.795	0.820	$<$ 0.001	0.131
Memory	3.06 $\pm$ 0.75	3.65 $\pm$ 0.95	3.25 $\pm$ 0.79	3.24 $\pm$ 0.83	0.153	0.568	$<$ 0.001	0.008
Attention	4.72 $\pm$ 0.89	5.03 $\pm$ 0.86	4.92 $\pm$ 0.96	4.88 $\pm$ 0.92	0.200	0.495	$<$ 0.001	0.519
Language	2.24 $\pm$ 0.75	2.43 $\pm$ 0.74	2.25 $\pm$ 0.76	2.28 $\pm$ 0.73	0.910	0.159	$<$ 0.001	0.245
Abstraction	1.47 $\pm$ 0.72	1.66 $\pm$ 0.56	1.59 $\pm$ 0.67	1.57 $\pm$ 0.72	0.328	0.568	$<$ 0.001	0.427
Orientation	5.26 $\pm$ 1.02	5.31 $\pm$ 0.96	5.37 $\pm$ 0.99	5.35 $\pm$ 1.03	0.551	0.658	0.536	0.797
Total GCS score	22.82 $\pm$ 7.48	18.76 $\pm$ 5.61	21.75 $\pm$ 8.38	21.37 $\pm$ 8.21	0.431	0.135	$<$ 0.001	0.033
Total MoCA score	22.75 $\pm$ 2.69	24.26 $\pm$ 2.98	23.35 $\pm$ 2.95	23.38 $\pm$ 2.98	0.373	0.805	$<$ 0.001	0.483

*Independent student t-test paired T-test

a: Between the two groups before the peatment b: Before and after the intervention in conpol group

c: Before and after the peatment in HRT group d: Between the two groups after the peatment

GCS: Green Climacteric Scale MoCa: Monpeal Cognitive Assessment HRT: Hormone Replacement Therapy