AIDS | Acquired immune deficiency syndrome |
AC | Adenylate cyclase |
BALF | Broncho-alveolar lung fluid |
BM-MSCs | Bone marrow-mesenchymal stem cells |
CC16 | Club cell-16 |
CDK9 | Cyclin-dependent kinase 9 |
COPD | Chronic obstructive pulmonary disease |
CS | Cigarette smoke |
CSE | Cigarette smoke extract |
CT | Computed tomography |
DAMPs | Damage-associated molecular patterns |
DPPIV | Dipeptidyl peptidase-4 |
ECLIPSE | Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points |
ECM | Extracellular matrix |
EPCs | Endothelial progenitor cells |
FDA | Food and drug administration |
FEV1 | Forced expiratory volume in one second |
FEV1/FVC FLAME |
Forced expiratory volume in one second/forced volume vital capacity EFfect of Indacaterol Glycopyronium Vs Fluticasone Salmeterol on COPD Exacerbations |
GAGs | Glycosaminoglycans |
GDP | Guanosine-5′-diphosphate |
GPCRs | G-protein coupled receptors |
GTP | Guanosine-5′-triphosphate |
16-HBE | 16-human bronchial epithelial cells |
HMGB1 | High mobility group box 1 protein |
HIV | Human immunodeficiency virus |
HPCs | Hematopoietic progenitor cells |
IFN-γ IMPACT |
Interferon-γ InforMing the PAthway of COPD Treatment |
IRF3 | IFN regulatory factor III |
IL | Interleukine |
IP3 | Inositol trisphosphate |
JAK/STAT | Janus kinase/signaling transducer and activator of transcription |
kDa | kilo Daltons |
LPS | Lipopolysaccharide |
MAPK/Erk | Mitogen activated protein kinase/extracellular signal-regulated kinase |
MCP-1 | Monocyte chemotactic protein 1 |
MMP | Matrix metalloproteinase |
PBMC | Peripheral blood mononucleated cells |
PI3K | Phosphoinositide 3-kinase |
PKC | Protein kinase C |
PLC | Phosphoinositide-specific phospholipase C |
PPE | Porcine pancreatic elastase |
PRRs | Pattern recognition receptors |
SNP | Single nucleotide polymorphism |
SP-D | Surfactant protein D |
sRAGE SUMMIT |
Soluble receptor for advanced glycation end-products Study to Understand Mortality and Morbidity in COPD |
TNF-α TORCH |
Tumor necrosis factor-α TOwards a Revolution in COPD Health |
TSG-6 UPLIFT |
TNF-stimulated gene/protein-6 Understanding Potential Long-term Impacts on Function with Tiotropium |
VEGF | Vascular endothelial growth factor |