Table 1.
Probit analysis showing the efficacy of carvacrol and thymol against Leishmania infantum promastigotes.
| Treatment | Concentration (µg/mL) | Growth Inhibition after 24 h (%) ± SE a | IC50 (µg/mL) (95% LCL–UCL) |
χ 2 b |
|---|---|---|---|---|
| Carvacrol | 10 | 50.3 ± 10.7 | 9.8 (65 μM) (8.51–11.7) |
1.29 n.s. |
| 5 | 25.6 ± 2.4 | |||
| 2.5 | 15.76 ± 1.6 | |||
| 1.25 | 6.66 ± 5.2 | |||
| Thymol | 10 | 62.76 ± 5.09 | 7.22 (48 μM) (6.22–8.62) |
3.37 n.s. |
| 5 | 41.13 ± 4.02 | |||
| 2.5 | 30.83 ± 2.24 | |||
| 1.25 | 14.93 ± 5.92 |
SE standard error, LCL 95% lower confidence limit, UCL 95% upper confidence limit, n.s. not significant (p ˃ 0.05). a values are mean ± SE of three replicates. b Chi-square value.