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. 2019 Jun 11;24(11):2190. doi: 10.3390/molecules24112190

Figure 1.

Figure 1

The effect of deep eutectic solvents (DES) on cell membrane permeability. The cations from the choline chloride and urea that form hydrogen bonds can disrupt the cell membrane, allowing the substrate to enter the cells, so then it can bind to the appropriate enzyme. Finally, the product can be released to the medium.