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TP53 allelic loss identified by array-comparative genomic hybridization (CGH) (upper line) was confirmed by interphase fluorescence in situ hybridization (iFISH) using LSPs (lower line). Results for two exemplary cases are shown: Image (A) shows heterozygous deletion of TP53 gene; image (B) shows monosomy of chromosome 17. Scale bars = 10 µm.
