Table 3.
Frequency of TP53 deletion in each histologic and WHO grading group.
| TP53 | All Cases | A-I | A-II | A-III | A-IV | OD-II | OD-III | OA-II | OA-III | ED-II | ED-III | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | % | N | % | N | % | N | % | N | % | N | % | N | % | N | % | N | % | N | % | N | % | |
| Intact | 46 | 70.8 | 5 | 55.6 | 9 | 90 | 4 | 66.7 | 16 | 66.7 | 3 | 100 | 0 | 0 | 2 | 100 | 1 | 50 | 3 | 75 | 3 | 75 |
| Hom. Del | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Het. Del | 19 | 29.2 | 4 | 44.4 | 1 | 10 | 2 | 33.3 | 8 | 33.3 | 0 | 0 | 1 | 100 | 0 | 0 | 1 | 50 | 1 | 25 | 1 | 25 |
| Total | 65 | 9 | 10 | 6 | 24 | 3 | 1 | 2 | 2 | 4 | 4 | |||||||||||
Hom. Del, homozygous deletion; Het. Del, heterozygous deletion; A, astrocytoma; OD, oligodendroglioma, OA, oligoastrocytoma, ED, ependymoma.