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Treatment with Lyc diminished the expression of MMP-9 and MMP-3. Rotenone-treated animals showed a significant increase in matrix metalloproteinases, MMP-9 (A) and MMP-3 (B). However, treatment with Lyc diminished the expression of MMP-9 and MMP-3 by virtue of its anti-inflammatory action. Histogram (C) represents densitometric analysis of western blots, and values are expressed as mean ± SEM. * p < 0.05 compared to control, # p < 0.05 compared to the rotenone-treated group.
