Figure 2.

Identification of predicted target genes of the MEG3- iodothyronine deiodinase 3 (DIO3) miRNA cluster. (A) Prediction frequency of the genes potentially targeted by the miRNAs in the MEG3-DIO3 locus; (B) The top seven predicted targets of the MEG3-DIO3 miRNA cluster and their known roles in mammalian cells; (C) Target prediction diagrams of protein phosphatase 2A (PP2A) subunit genes by the MEG3-DIO3 miRNA cluster. A total of one scaffolding subunit gene and six regulatory subunit genes were predicted.