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The dose-dependent inhibition of plasmin-mediated clot lysis by pentamidine isethionate. The effect was determined by measuring the ultraviolet (UV) absorbance of each well containing different concentration of pentamidine at 405 nm over a time period of 340 min. Solid line represents the sigmoidal dose–response fits (Equation (1)) for the data to obtain the values of IC50, HS, and ΔY (%). Given also are the standard error bars (±1 SE).
