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. 2019 Jun 4;24(11):2109. doi: 10.3390/molecules24112109

Figure 5.

Figure 5

Secreted cytokines profiling and nitric oxide release. Cytokines (G-CSF, GM-CSF, IL-6, IL-8, MCP-1, and VEGF) release following CrataBL treatment with 50 µM and 100 µM after 24 h in the media of (A) MSC, U87 glioblastoma cells, and cocultured cells. Nitric oxide release was analyzed by chemiluminescence in (B) MSC, U87 glioblastoma cells, and cocultured cells after 24 h and 48 h of CrataBL treatment (50 µM and 100 µM), compared to nontreated controls (c). Significance was considered at * p < 0.05, ** p < 0.005, and *** p < 0.0005.