Figure 5.

(A) depicts that ligand binding affinity of monomer (purple) increases in the presence of its partner protomer (orange); (B) ligand efficacy of monomer (purple) decreases (middle) or increases (right) in the presence of its partner (orange) when they form dimer; (C) functional selectivity of dimer changes in the presence of protomer; concurrently, G protein is substituted with $\beta$-arrestin.