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. 2019 Jun 5;20(11):2761. doi: 10.3390/ijms20112761
amyloid-β
AβO amyloid-β oligomer
PS1 presenilin 1
eIF2α eukaryotic translation initiation factor 2α
GADD34 growth arrest and DNA damaged-inducible gene 34
ATF4 activating transcription factor 4
AD Alzheimer’s disease
APP Aβ precursor protein
ER endoplasmic reticulum
PKR double-stranded RNA-activated protein kinase
PERK PKR-like ER-localized eIF2α kinase
GCN2 general control nonderepressible-2
HRI heme-regulated inhibitor
CREB2 cAMP response element binding protein 2
ISR integrated stress response
GTP guanosine triphosphate
PP1c protein phosphatase 1c
CReP constitutive repressor of eIF2α phosphorylation
ApoE apolipoprotein E
Atg5 autophagy-related 5
ISRIB ISR inhibitor
GEF guanine nucleotide exchange factor
NSCs neural stem cells
SVZ subventricular zone
SGZ hippocampal subgranular zone
iPSCs induced pluripotent stem cells
REST repressor element 1-silencing transcriptional factor
BDNF brain-derived neurotrophic factor
FNDC5 fibronectin type III domain-containing protein 5
DCX doublecortin
LV lateral ventricle
MCI mild cognitive impairment
IRE1 inositol-requiring enzyme 1
XBP1 X-box binding protein 1