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. 2019 Jun 11;20(11):2840. doi: 10.3390/ijms20112840

Figure 1.

Figure 1

Mechanisms of extracellular vesicle (EV) release and their specific markers. Apoptotic bodies (ApoBDs) are released by membrane blebbing of apoptotic cells; microvesicles (MVs) bud directly from the plasma membrane of living cells, while exosomes are formed as the intraluminal vesicles (ILVs) by budding into early endosomes and multivesicular bodies (MVBs) and are released by exocytosis. PS: phosphatidylserine; MHC: major histocompatibility complex; TSG101: tumor susceptibility gene 101 protein; HSP70: heat shock 70 kDa protein.