Figure 5.

Infarct zones of sheep treated with cells express higher levels of active YAP1 when compared with non-infarcted regions as shown by PCR (A). YAP1 protein concentration was elevated compared to non-infarcted regions, confirming the PCR results (B). The ratio of phosphorylated YAP1 to non-phosphorylated YAP1 declined in the infarcted region of the heart compared to the non-infarcted region (C). Western blot image shows change in concentration of phosphorylated and non-phosphorylated YAP1 (D). n = 3, * p < 0.05, *** p < 0.001, **** p < 0.0001. Fold changes are shown as the mean ± SEM. All samples were run in triplicate.