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. 2019 Jun 4;24(11):2115. doi: 10.3390/molecules24112115

Table 3.

Performance statistics for failed NBNs generated with the specified error in each split.

Model %Error Failure ROC AUC Top 10% Mean IC50 (nM) Mean IC50 (nM) Bottom 10% Mean IC50 (nM) Fold Difference in Mean Top 10% IC50
ALK < 20 nM NBN Control 0.917 6.70 4200 17,000 2500
Split 1 Error 45 0.674 1400 4200 4900 3.5
Split 2 Error 45 0.632 900 3300 8100 9.0
Split 3 Error 50 0.539 2400 4100 1100 0.46