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. 2019 Jun 4;24(11):2115. doi: 10.3390/molecules24112115

Table 4.

Performance statistics for NBNs with retained predictivity generated with the specified error in each split.

Model %Error Before Failure ROC AUC Top 10% Mean IC50 (nM) Mean IC50 (nM) Bottom 10% Mean IC50 (nM) Fold Difference in Mean Top 10% IC50
ALK < 20 nM NBN Control 0.917 6.70 4200 17,000 2500
Split 1 Pre-failure 40 0.742 53.5 4200 3100 58
Split 2 Pre-failure 40 0.747 275 3300 9200 33
Split 3 Pre-failure 45 0.703 130 4100 4500 35