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Performance statistics for failed PNNs generated with the specified error in each split.
| Model | %Error Failure | ROC AUC | Top 10% Mean IC50 (nM) | Mean IC50 (nM) | Bottom 10% Mean IC50 (nM) | Fold Difference in Mean Top 10% IC50 |
|---|---|---|---|---|---|---|
| ALK < 20 nM PNN | Control | 0.782 | 34.7 | 4200 | 19,000 | 550 |
| Split 1 Error | 20 | 0.654 | 726 | 4200 | 12,000 | 17 |
| Split 2 Error | 30 | 0.615 | 287 | 3300 | 7600 | 26 |
| Split 3 Error | 15 | 0.635 | 1200 | 4100 | 3300 | 2.8 |
