Table 9.

Summary of points of failure for each algorithm, random split and target.

Target	Algorithm	Split 1 Percent Error of Failure	Split 2 Percent Error of Failure	Split 3 Percent Error of Failure	Mean Percent Error of Failure
ALK	NBN	45	45	50	47
	RF	30	40	40	37
	PNN	20	30	50	33
Aurora B	NBN	30	30	35	32
	RF	20	20	25	22
	PNN	-	-	-	-
β-2	NBN	50	50	50	50
	RF	35	25	45	35
	PNN	10	20	5	12
c-Abl	NBN	45	50	45	47
	RF	35	25	35	32
	PNN	30	25	15	23
Factor Xa	NBN	35	45	45	42
	RF	30	30	30	30
	PNN	20	10	30	20
HIV Protease	NBN	50	45	50	48
	RF	35	20	15	23
	PNN	25	15	25	22
JAK2	NBN	40	30	40 *	35
	RF	40	30	35	35
	PNN	-	-	-	-
MEK1	NBN	40	30	40	37
	RF	30	35	25	30
	PNN	5	5	25 **	12
PARP1	NBN	5	45	50	33
	RF	40	25	40	35
	PNN	25 **	5	25 **	18
TYRO3	NBN	30	10	5	15
	RF	20	5	5 *	10
	PNN	-	-	-	-

* failed in the control step, therefore another random split was used. ** reparameterization shifted the point of failure.