Skip to main content
. 2019 Jan 17;104(7):1460–1472. doi: 10.3324/haematol.2018.194555

Figure 2.

Figure 2.

GFI1B and GFI1BQ287* regulate MEG-01 expansion via LSD1 recruitment. (A) Normalized GFP percentages (GFP%) of MEG-01 cells transduced with empty vector (EV)-IRES-GFP, GFI1B-IRES-GFP and GFI1BQ287*-IRES-GFP for 26 days (n=8). GFP% were normalized to day 5 after transduction (starting point of the culture) as described in the Methods. Results are shown as the mean ± standard error of the mean. (B) Normalized GFP% of MEG-01 cells transduced with EV-IRES-GFP, GFI1B-IRES-GFP, and GFI1BP2A-IRES-GFP (n=4). (C) Normalized GFP% of MEG-01 cells transduced with EV-IRES-GFP, GFI1B-IRES-GFP, and GFI1BK8A-IRES-GFP (n=3). (D) Normalized GFP% of MEG-01 cells transduced with EV-IRES-GFP, GFI1BQ287*-IRES-GFP, and GFI1BP2A+Q287*-IRES-GFP (n=3). (E) Normalized GFP% of MEG-01 cells transduced with EV-IRES-GFP, GFI1BQ287*-IRES-GFP, and GFI1BK8A+Q287*-IRES-GFP (n=4). *P<0.05, **P<0.01 ***P<0.001.