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. 2019 May 6;25:83–94. doi: 10.1016/j.molmet.2019.05.002

Figure 7.

Figure 7

Loss of ABHD15 resulted in elevated liver lipid in response to β-adrenergic receptor agonist in mice. A, Liver triglycerides (TG) were measured in untreated (Ø) wild type and ABHD15−/− (KO) mice (n = 20–22) or ∼16 h after CL316,243 (CL) injection (n = 8–10). B, Plasma fatty acids were measured before and 10 min after CL316,243 injection (n = 8–10). C, Representative photograph of livers from wild type and ABHD15−/− mice ∼16 h after CL316,243 injection is shown. D, Brown adipose tissue (BAT) triglycerides were measured ∼16 h after CL316,243 injection (n = 4). Data are mean ± SEM with individual data points shown; # different from WT, #p < 0.05, ####p < 0.0001; §§§§ different from 0 min (B) or Ø (A) p < 0.0001; statistical significance was determined using two-way ANOVA with Sidak's multiple comparison test (A-B) or one-tailed t-test (C).