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. 2019 Jun 18;18(2):1458–1464. doi: 10.3892/etm.2019.7689

Figure 1.

Figure 1.

miR-876-5p suppresses breast cancer cell proliferation. (A) RT-qPCR analysis demonstrated that miR-876-5p level was downregulated in breast cancer cell lines. (B) RT-qPCR analysis for miR-876-5p expression following transfection with miR-876-5p mimics, miR-876-5p inhibitors or negative controls. Cell Counting Kit-8 assays revealed that miR-876-5p mimics suppress proliferation of (C) MCF-7 and (D) T47D cells. (E) Western blot analysis indicated that miR-876-5p mimics suppress the expression of Cyclin D1 in MCF-7 and T47D cells. *P<0.05 with comparisons indicated by lines. miR, microRNA; RT-qPCR, reverse transcription-quantitative PCR; OD, optical density.