Regulatory effects of miR-877 upregulation on the proliferation and invasiveness of H460 and A549 cells. (A) miR-877 mimics or miR-NC were transfected into H460 and A549 cells, and upregulation of miR-877 was confirmed by reverse transcription-quantitative PCR. (B) Effect of miR-877 overexpression on the proliferative ability of H460 and A549 cells evaluated using a CCK-8 assay. (C) Transwell invasion assays were used to determine the invasion of H460 and A549 cells following transfection of miR-877 mimics or miR-NC (magnification, ×200). *P<0.05 vs. miR-NC. CCK-8, Cell Counting kit-8; miR-877, microRNA-877; miR-NC, microRNA mimics negative control; OD, optical density.