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. Author manuscript; available in PMC: 2020 Jun 30.
Published in final edited form as: Biochem Biophys Res Commun. 2019 May 12;514(3):974–978. doi: 10.1016/j.bbrc.2019.05.064

Fig. 1. HIV PR dimer with sites of mutations and selected inhibitors.

Fig. 1.

A) Sites of mutation in HIV-1 PR dimer with inhibitor GRL-1111. PR is shown as green ribbons with sites of the three mutations, V32I, I47V and V82I, indicated as grey spheres. Inhibitor is shown in red sticks.

B) Structures of darunavir and investigational inhibitors. The P2-P2’ groups are indicated for DRV. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)