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. Author manuscript; available in PMC: 2020 Jun 30.
Published in final edited form as: Biochem Biophys Res Commun. 2019 May 12;514(3):974–978. doi: 10.1016/j.bbrc.2019.05.064

Fig. 4. Interactions of alternative conformations of Arg8′ with neighboring side chains and inhibitor.

Fig. 4.

A) Mutant PRTri is shown in magenta sticks with alternate conformation of Arg8’ in cyan and inhibitor 1 in green. Wild type PR and inhibitor are grey. Dotted lines indicate ionic interaction, and dashed lines indicate hydrophobic interactions. CH-p interactions with the aromatic P1 group of inhibitor are indicated by a single dashed line. B) Mutant PRTri in peach bonds with DRV in yellow sticks. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)