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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Biochem Biophys Res Commun. 2018 May 9;501(1):172–177. doi: 10.1016/j.bbrc.2018.04.207

Figure 1. LPS-stimulated human PBMCs expresses TF and initiates thrombin generation.

Figure 1

Human PBMCs were treated with PBS or 100 ng/ml LPS at 37°C for 4 hours, the expression of TF on PBMCs were analyzed by flow cytometry using PE-labeled anti-TF antibody (A). Thrombin generation initiated by PBMCs was performed as described in the Materials and Methods. PBMCs were treated with PBS, 100 ng/ml LPS, or 100 ng/ml LPS plus 50 μg/ml anti-TF antibody (4501) (n=3). Representative trace (B) and peak thrombin generation are shown (C). **P < 0.01, ***P < 0.001, t test.