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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Circ Genom Precis Med. 2019 May 6;12(6):e002390. doi: 10.1161/CIRCGEN.118.002390

Figure 5.

Figure 5.

Effect of ART drugs on cholesteryl ester (CE) accumulation in THP-1 foam cells. CE accumulation was measured in cell lysates of THP-1-derived macrophages pre-treated with DMSO (−), nelfinavir, saquinavir, ritonavir, maraviroc (5, 15 and 30 μM), and raltegravir (5 and 30 μM) for 24 hours and then incubated with AcLDL (50 μg/mL) for additional 48 hours. Drug treatment was maintained throughout the experiment. Results are shown for 3 independent experiments with 3 technical replicates (n=9). Data are expressed as mean±SEM.