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. 2019 Jun 4;18(2):1189–1195. doi: 10.3892/etm.2019.7642

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Copyright: © Chang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Expression of miR-590-5p in NSCLC tissues and effect of miR-590-5p on cell migration and epithelial-to-mesenchymal transition-associated protein expression. (A) The expression of miR-590-5p was significantly associated with pathological stage in 33 patients. (B) The expression of miR-590-5p was associated with lymph node metastasis in NSCLC. (C and D) Densitometric analysis of western blot analysis data of E-cadherin, vimentin, Snail and Slug expression. (D) Representative western blot analysis gel performed in A549 cells transfected with miRNA NC, miR-590-5p mimics, miR-590-5p mimics + SOX2 overexpression. *P<0.05. SOX2, sex determining region Y-box 2; NSCLC, non-small-cell lung cancer; miRNA/miR, microRNA; OE, overexpression; E-cadherin, epithelial cadherin; Snail, zinc finger protein SNAI1; Slug, zinc finger protein SNAI2; NC, negative control.