FIG A3.

Kaplan-Meier curve for time to first nonadherent study visit according to treatment arm. Numbers in parentheses represent the number of events that occurred within each time interval by treatment arm. The log-rank test was used to draw inferences. Overall, 62.8% of women were adherent for at least 2.5 years. The mean time on treatment was 2.3 years (standard deviation, 1.1). Kaplan-Meier estimate for adherence was not significantly different in women who took tamoxifen (64.8%) compared with those who took placebo (60.7%). Overall, dropout rates were highest within the first 6 months since randomization (10.3% in the tamoxifen arm; 12.2% in the placebo arm) and decreased thereafter. HR, hazard ratio.