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. 2019 Jul 1;33(13-14):747–762. doi: 10.1101/gad.321059.118

Figure 2.

Figure 2.

Deletion of Tle3 in adipocytes improves glucose handling with cold exposure. (A) GTT and AUGg on control (Tle3F/F) and knockout (Tle3F/F Adipoq-Cre) mice after 1 wk at thermoneutrality (30°C). n = 6–7 per group. (B) GTT and AUCg following 4 d in cold (4°C). n = 6–7 per group. (C) ITT and AUCg on Tle3F/F and Tle3F/F Adipoq-Cre mice after 1 wk at thermoneutrality and cold. n = 6–7 per group. (D) ITT and AUCg following 4 d in the cold (4°C). n = 6–7 per group. (E) Change in measured AUCg for GTT and ITT from thermoneutrality to after cold exposure. (F) Uptake of 2-[U-14C]-deoxyglucose in BAT, iWAT, and eWAT for Tle3F/F and Tle3F/F Adipoq-Cre mice following 4 d of cold exposure. n = 4 per group. Data are presented as mean ± SEM. Significance was analyzed by two-tailed Student's t-test. (*) P < 0.05.