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. 2019 May 8;11(5):826–836. doi: 10.1080/19420862.2019.1608143

Figure 7.

Figure 7.

Comparison of structural stabilities of the CH2 domain of glycoengineered anti-CD20 mAbs using HDX/MS. Deuterium uptake plots of peptides Phe245–Leu255 (FLFPPKPKDTL) (a), Leu246–Leu255 (LFPPKPKDTL) (b), and Leu246–Met256 (LFPPKPKDTLM) (c) in the H-chain. (d) Physical representations of the crystal structures (PDB 1HZH) of peptides at Phe245–Met256 (magenta ribbons).